Joseph baur, Ph.D.

Assistant Professor, Perelman School of Medicine, University of Pennsylvania.

Dr. Baur was the first to show that resveratrol, a small molecule with many effects, including activation of the sirtuin SIRT1, is able to improve insulin sensitivity and extend lifespan in obese mice.  He earned his Ph.D. from the University of Texas Southwestern, where he studied mechanisms that limit the lifespan of cultured human cells. He trained as a postdoctoral fellow with Dr. David Sinclair at Harvard Medical Schoool, where he developed a strong interest in the regulation of aging and metabolism by sirtuins, a conserved class of enzymes that regulate lifespan in lower organisms.

 

Marina Holz, ph.D.

Professor, Doris and Ira Kukin Chair in Biology, Yeshiva University and the Albert Einstein Cancer Center, Albert Einstein College of Medicine 

Dr. Holz’ research is focused on the interaction between the mechanistic target of rapamycin (mTOR) pathway & estrogen receptor signaling in various diseases including lymphangioleiomyomatosis (LAM) and breast cancer. Dr. Holz has an interest in combination therapies in clinic, including the co-administration of resveratrol with rapamycin (sirolimus).  Dr. Holz received her Bachelors of Science degree from McGill University in Montreal, Canada. She completed her Ph.D. in Cell Biology at Harvard Medical School.